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Flowable collagen-based hemostat and methods of use
专利权人:
Marissa M. Darmoc
发明人:
Marissa M. Darmoc,Lauren S. Brown,Jenny E. Raynor,Alice Chou,Abigail Cohen
申请号:
US13411324
公开号:
US09447169B2
申请日:
2012.03.02
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The invention relates to hemostatic compositions and methods for promoting hemostasis. The invention also relates to hemostatic compositions and methods for promoting wound healing. In various embodiments, the hemostatic compositions comprise crosslinkable collagen molecules having a porosity controlled by the ratio of weight percent collagen solids to weight percent crosslinker when crosslinking the collagen. In other embodiments, the hemostatic compositions comprise crosslinkable collagen molecules having a porosity controlled by the temperature and rate of freezing when drying the composition during fabrication. In some embodiments, the compositions contain additional agents, including biological agents.
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