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Small molecule composite surfaces as inhibitors of protein-protein interactions
专利权人:
Roger Briesewitz
发明人:
Roger Briesewitz,Dehua Pei,Xianghong Wu
申请号:
US14126343
公开号:
US09260484B2
申请日:
2012.06.15
申请国别(地区):
US
年份:
2016
代理人:
摘要:
A method of inhibiting a binding event between a target protein and a binding protein, comprising administering to a cell in vitro an effective amount of a non-naturally occurring bifunctional inhibitor molecule including (a) protein binding moiety, and (b) an effector region, wherein the protein binding moiety binds to a blocking protein, and wherein the effector region binds to the target protein in order to bind the target protein and the blocking protein and prevent access of the binding protein to the target protein. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
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