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Oxadiazolidinedione compound
专利权人:
アステラス製薬株式会社
发明人:
根来 賢二,岩▲崎▼ 史良,大貫 圭,黒崎 寿夫,米▲徳▼ 康博,朝井 範夫,吉田 茂,曽我 孝利
申请号:
JP2008512175
公开号:
JP5309991B2
申请日:
2007.04.23
申请国别(地区):
JP
年份:
2013
代理人:
摘要:
[Problem] A compound which can be used as a pharmaceutical, particularly a insulin secretion promoter or a agent for preventing/treating disease in which GPR40 is concerned such as diabetes or the like, is provided. [Means for resolution] It was found that an oxadiazolidinedione compound which is characterized by the possession of a benzyl or the like substituent binding to the cyclic group via a linker at the 2-position of the oxadiazolidinedione ring, or a pharmaceutically acceptable salt thereof, has excellent GPR40 agonist action. In addition, since the oxadiazolidinedione compound of the present invention showed excellent insulin secretion promoting action and blood glucose level-lowering action, it is useful as an insulin secretion promoter or an agent for preventing/treating diabetes.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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