The present invention relates to an anti-human ±9 integrin antibody. More particularly, the present invention relates to: a monoclonal antibody, a chimeric antibody, a humanized antibody and a human antibody that specifically recognize human ±9 integrin; a hybridoma cell that produces the monoclonal antibody; a method for producing the monoclonal antibody; a method for producing the hybridoma cell; a therapeutic agent comprising the anti-human ±9 integrin antibody; a diagnostic agent comprising the human ±9 integrin antibody; and a method for screening for a compound that inhibits the activity of human ±9 integrin.