#$%^&*AU2017204355A120180125.pdf#####ABSTRACT An alloprosthetic composite implant is disclosed comprising a structural porous scaffold having a pore density profile corresponding to a density profile of bone to be replaced. A plurality of cells including osteoblasts and/or stem cells, are seeded within pores of the porous scaffold and grown by incubation. Further one or more cartilage layers may be grown on top of the scaffold. The pore density profile of the scaffold that is formed may be based on the bone density profile of the bone to be removed, and/or the bone density profile of the native bone that will be in contact with the alloprosthetic implant. A robot may be employed to resect the native bone and also to shape the alloprosthetic implant to fit into place in the native bone. Figure for publication 7100 24 FIG. 3
