Jørn Dalgaard Mikkelsen,Carsten Jers,Malwina Michalak,Kasper Planeta Kepp,Dorte Møller Larsen
申请号：
US14783967
公开号：
US10081801B2
申请日:
2014.04.11
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The invention provides a mutant enzyme having trans-sialidase activity (EC 3.2.1.18), characterized by an enhanced trans-sialidase:sialidase ratio when compared to its parent sialidase enzyme. Further the enzyme may be used in a method for trans-sialylating mono- and oligo-saccharides, including galacto-oligosaccharides (GOS), fructo-oligosaccharides (FOS), malto-oligosaccharides (MOS), isomalto-oligosaccarides (IMO), lactulose, melibiose, maltose, glycosyl sucrose, lactosucrose and fucose. Trans-sialidated mono- and oligo-saccharides, produced with the mutant enzyme, are useful in preparing infant formula, a prebiotic nutritional supplement, and a food supplement.
