Combined brachytherapy and ablation devices and methods. A combined brachytherapy and cryotherapy method, includes: inserting an ablation device into tissue of a subject ablating tissue within an ablation zone of the device detaching and removing a first part of the device while leaving a second part of the device in the tissue, the first part contacting the ablation zone and inserting a brachytherapy rod into the second part of the device when the second part is detached from the first part, the brachytherapy rod connected to base at one end and retaining at least one radioactive seed at an opposing end, the brachytherapy rod configured and dimensioned so that when it is inserted into the device up to the base, the at least one radioactive seed is in the ablation zone.
