A patient warming and deep vein thrombosis system are provided. The system includes a first and a second compliant layer sealed together around an outer border to contain a warm liquid between the two layers and to form a wrap to surround and conform to a body portion of a patient. The wrap includes a plurality of flaps extends from opposite sides of a generally longitudinal central portion, such that one or more flaps from the opposite sides fasten to each other to surround the body portion. The flaps are openable during functional use to provide access to an underlying patient body surface. The system also includes a fluid control pump that directs the liquid through a continuous fluid flow path that extends between the two layers so as simultaneously to fill the wrap and apply pressure and heat to the body portion surrounded by the wrap.