BRAHMBHATT HIMANSHU,MACDIARMID JENNIFER,Brahmbhatt Himanshu,Macdiarmid Jennifer
申请号：
SI200531962
公开号：
SI2386640T1
申请日:
2005.08.25
申请国别(地区):
SI
年份:
2015
代理人:
摘要：
Intact bacterially derived minicells containing functional nucleic acids or plasmids encoding functional nucleic acids can reduce, in targeted mammalian cells, drug resistance, apoptosis resistance, and neoplasticity, respectively. Methodology that employs minicells to deliver functional nucleic acids, targeting the transcripts of proteins that contribute to drug resistance or apoptosis resistance, inter alia, can be combined with chemotherapy to increase the effectiveness of the chemotherapy.
