David WATKINS,Alexander OKSCHE,Kevin SMITH,Helkki MANSIKKA,Paul BAILEY
申请号：
US14894775
公开号：
US20160106736A1
申请日:
2014.05.30
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present invention provides a method of providing pain relief in a human subject in need thereof comprising administering (R)-dihydroetorphine to said subject, wherein said (R)-dihydroetorphine is administered in a dose of at least 0.01 μg/kg, preferably at least 0.05 μg/kg, and the level of respiratory depression in said subject is 65 or less % relative to the baseline level pre-administration of (R)-dihydroetorphine.
