PROBLEM TO BE SOLVED: To provide a pharmaceutical combination useful for the treatment of the indications for opioid use, for example pain from various etiologies.SOLUTION: A pharmaceutical combination of opioid and prostaglandin compounds is provided.SELECTED DRAWING: None【課題】オピオイド使用の適応症、例えば様々な病因による痛みに有用な医薬的組み合わせの提供。【解決手段】オピオイドおよびプロスタグランジン化合物の医薬的組み合わせ。【選択図】なし