A proprioceptive enhancement device, including methods of use, is described. The proprioceptive enhancement device includes a sock-like garment, with or without a shoe or other footwear, which mechanically and electrically stimulates cutaneous, subcutaneous, and deep tissue mechanoreceptors and proprioceptors to provide feedback to the user. The feedback causes the user to adjust weight distribution during athletic and non-athletic activities for optimal performance and increased overall health. The device includes additional configurations for electrically grounding the wearer to the earth, which may provide additional health benefits. The disclosure includes a method of using the proprioceptive enhancement device to treat wounds of the foot, including but not limited to venous stasis ulcers, arterial insufficient ulcers, traumatic wounds, and the like.