DRAKE, PHILLIP ASA,PENG, RUZHAN,DECKNER, GEORGE ENDEL
申请号：
CA2773162
公开号：
CA2773162C
申请日:
2010.09.01
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
Comparative effectiveness of various oral care products such as dentifrices on preventing dental erosion may be demonstrated using simulated enamel. A substrate is prepared. A mineral layer to simulate dental enamel is nucleated by solution growth on the substrate surface. Alternatively, the mineral layer may be nucleated on a template comprising a self-assembled monolayer formed on a gold layer deposited on the substrate surface. The mineral layer may comprise a homogeneous layer of hydroxyapatite or a thin veneer of hydroxyapatite on a layer of amorphous calcium phosphate. The simulated enamel is then optionally treated with an oral care product and subjected to an acid challenge. The amount of mineral layer remaining after the acid challenge dramatically illustrates the effectiveness or non-effectiveness of the oral care product at preventing dental erosion.
