Use of human serum albumin to decrease antigenicity of therapeutic proteins

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专利权人:

Protox Therapeutics Corp.

发明人:

Merchant, Fahar

申请号：

AU2011316786

公开号：

AU2011316786A1

申请日:

2011.10.24

申请国别(地区):

AU

年份:

2013

代理人:

摘要：

Provided herein are therapeutic compositions that include albumin (such as human serum albumin) and therapeutic proteins, such as a modified proaerolysin protein or an apoptosis-modulating fusion protein, as well as kits that include such compositions in containers. Also provided are methods of using such compositions in decreasing the antigenicity of therapeutic proteins such as modified proaerolysin proteins or apoptosis-modulating fusion protein antibodies (for example as evidenced by a decrease in the production of neutralizing antibodies).

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/