A rectal medication administration device includes a tube, a balloon, a first valved port, and a second valved port. The tube includes a first lumen, a second lumen, and a plurality of holes extending from the first lumen therethrough. The balloon is proximal to the holes, is in communication with the second lumen, and is configured to be inflated to hold the tube in place within a patients rectum. The first valved port is in communication with the first lumen and opens when connected to a first syringe or infusion set to provide medication transmission therethrough and closes when the first syringe or infusion set is withdrawn. The second valved port is in communication with the second lumen and opens when connected with a second syringe or infusion set to provide fluid to inflate the balloon and closes when the second syringe or infusion set is withdrawn.
