The purpose of the present invention is to provide a prophylactic or treating agent of non-steroidal anti-inflammatory drugs and proton pump inhibitors induced small intestinal injury.The present invention provides a prophylactic or treating agent of non-steroidal anti-inflammatory drugs and proton pump inhibitors induced small intestinal injury or lipid-related diseases and/or inflammations accompanying with the above small intestinal injury, wherein the agent comprises bifidobacterium bifidum, bifidobacterium longum or bifidobacterium infantis or treated products thereof.本發明之目的，為提供一種非類固醇性抗炎症藥及氫離子幫浦抑制劑誘發性小腸損傷之預防或治療劑。本發明提供一種非類固醇性抗炎症藥及氫離子幫浦抑制劑誘發性小腸損傷及伴隨該小腸損傷之脂肪相關疾病及/或炎症的預防或治療劑，包含雙叉雙歧桿菌(Bifidobacterium bifidum)、長雙歧桿菌(Bifidobacterium longum)或嬰兒雙歧桿菌(Bifidobacterium infantis)或其處理物。
