The purpose of the present invention is to provide a prophylactic or treating agent of NSAIDs having a half-life less than 14 hours and proton pump inhibitors-induced small intestinal injury.The present invention provides a prophylactic or treating agent of NSAIDs having a half-life less than 14 hours and proton pump inhibitors-induced small intestinal injury or lipid-related diseases and/or inflammations accompanying with the above small intestinal injury, wherein the agent comprises bifidobacterium sp. bacteria or treated products thereof.本發明之目的為提供半減期未達14小時之NSAIDs及氫離子幫浦抑制劑誘發性小腸損傷之預防或治療劑。本發明提供一種半減期小於14小時之非類固醇性抗炎症藥及氫離子幫浦抑制劑誘發性小腸損傷及伴隨該小腸損傷之脂肪相關疾病及/或炎症的預防或治療劑，其包含雙歧桿菌屬之菌或其處理物。
