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POLYMORPH VON DPPIV-INHIBITOR-MALEAT UND HERSTELLUNGSVERFAHREN DAFÜR
专利权人:
Shanghai Institute of Materia Medica; Chinese Academy of Sciences
发明人:
LIU, Hong,WANG, Jiang,LI, Jian,LI, Jia,LI, Jingya,JIANG, Hualiang,LUO, Xiaomin,CHEN, Kaixian
申请号:
EP17769393
公开号:
EP3434677A4
申请日:
2017.03.20
申请国别(地区):
EP
年份:
2019
代理人:
摘要:
A polymorph of (R) methyl-2-(3-aminopiperidin-1-yl)-3-(2-cyanobenzyl)-4-carbonyl-3,4-dihydrothioph ene[3,2-d]pyrimidine-6-carboxylic acid maleate and a preparation method therefor. The polymorph is a crystal having high stability and low hygroscopicity, and the crystal form is selected from crystal form A, crystal form B and crystal form C. Furthermore, the crystal form has a strong in-vivo hypoglycemic activity and can be used for the preparation of a novel drug for the treatment or prevention of diabetes mellitus type H and/or complications of diabetes mellitus type H.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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