Harsh M. Trivedi;Tao Xu;Davide Miksa;Cortney Worrell;Chanda Macias;Ying Yang;Yanan Hu
发明人:
Harsh M. Trivedi,Tao Xu,Davide Miksa,Cortney Worrell,Chanda Macias,Ying Yang,Yanan Hu
申请号：
US13258142
公开号：
US10426752B2
申请日:
2009.04.01
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present invention discloses novel uses of specific menthol-derivative compounds of Formula 1, and compositions thereof, for methods of providing oral and systemic health care benefits, and methods of up-regulating or down-regulating periodontal disease metabolites: Formula 1 wherein, X is an oxygen atom or an NH radical； and R is an unsubstituted or substituted aryl or aliphatic radical. In some embodiments, the oral and systemic health care benefits include biofilm anti-attachment, anti-inflammation, anti-oxidant, anti-bone loss, and anti-microbial benefits. In some embodiments, the periodontal disease metabolites correspond to healthy and/or diseased oral status and allow differential diagnosis of oral health.
