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METHODS AND COMPOSITIONS FOR RNA-GUIDED TREATMENT OF HIV INFECTION
专利权人:
发明人:
Kamel KHALILI,Wenhui Hu
申请号:
US15884428
公开号:
US20180169195A1
申请日:
2018.01.31
申请国别(地区):
US
年份:
2018
代理人:
摘要:
A method of treating a subject having or at risk for having a virus infection, by administering to the subject a therapeutically effective amount of a composition comprising a vector encoding a CRISPR-associated endonuclease and at least two guide RNAs, wherein the guide RNAs are complementary to two target sequences spanning from the 5′- to 3′-LTRs of the sequence in the virus, and completely resolving the symptoms of a disease, decreasing the severity of the symptoms of the disease, or slowing the diseases progression.
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