Ali EHSANI;Pal SAETROM;Ola SNOVE, JR.;Britta HOEHN;John J. ROSSI;Lars AAGAARD;Jane ZHANG
发明人:
John J. ROSSI,Ola SNOVE, JR.,Ali EHSANI,Pal SAETROM,Britta HOEHN,Jane ZHANG,Lars AAGAARD
申请号:
US13287493
公开号:
US20120046343A1
申请日:
2011.11.02
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates to novel short interfering RNA (siRNA) molecules that are multi-targeted. More specifically, the present invention relates to siRNA molecules that target two or more sequences. In one embodiment, multi-targeting siRNA molecules are designed to incorporate features of siRNA molecules and features of micro-RNA (miRNA) molecules. In another embodiment, multi-targeting siRNA molecules are designed so that each strand is directed to separate targets.