The present disclosure provides a method for manufacturing an excellent denatured whey protein having no adverse effect on the characteristics of a product. A method for manufacturing a denatured whey protein comprising processing a whey protein solution by repeating the following steps (1) and (2) 2 times or more continuously: (1) a step for homogenizing the whey protein solution in less than 3 seconds on pressure at 50 MPa or higher and on heating at 85 to 100oC and, (2) a step for decompressing to 0.05 to 0.5 MPa after the step (1) and maintaining the whey protein solution at 0.05 to 0.5 MPa in the range of the heating temperature of the step (1) 10oC and in less than 1.34 minutes.