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COMPOSE DE CYCLOPROPANE
专利权人:
EISAI R&D MANAGEMENT CO.; LTD.
发明人:
TERAUCHI, TARO,TAKEMURA, AYUMI,DOKO, TAKASHI,YOSHIDA, YU,TANAKA, TOSHIAKI,SORIMACHI, KEIICHI,NAOE, YOSHIMITSU,BEUCKMANN, CARSTEN,KAZUTA, YUJI
申请号:
CA2811895
公开号:
CA2811895C
申请日:
2011.09.20
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
A cyclopropane compound represented by the following formula (A) or apharmaceutically acceptable salt thereof has orexin receptor antagonism, andtherefore has apotential use for the treatment of sleep disorder for which orexin receptorantagonism iseffective, for example, insomnia:(see formula A)wherein Q represents -CH- or a nitrogen atom, R1a and R1b each independentlyrepresent a C1-6alkyl group and the like, R1c represents a hydrogen atom and the like, R2a,R2b, R2c and R2d eachindependently represent a hydrogen atom, a halogen atom, a C1-6 alkyl groupand the like, R3a,R3b and R3c each independently represent a hydrogen atom, a halogen atom andthe like, and R3drepresents a hydrogen atom and the like.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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