A pharmaceutical low dose, antibiotic combination of two antibiotics selected from a carbapenem and an aminoglycoside, present as a single unit fixed low dose injection effective at very low concentrations. The antibiotic combination is suitable for the treatment of bacterial/multibacterial infections, and is particularly suitable for neonates, children, and other patients with low tolerance, and who are prone to serious fatal mixed multi-bacterial infectious diseases where potential toxicity due to higher doses is a cause for concern.