An electro-hydro massage device enhances the therapeutic benefits of electrical nerve and muscle stimulation by incorporating simultaneous tactile and thermal stimulation from water flow, using a hand-held source of electric current and water flow, in contact with the users skin. The water flow also reduces the skins resistance to electrical current and provides warming or cooling to complement and enhance effects of the electrical stimulation. The treatment surface of the hand-held electro-hydro massage device contacts the users skin and contains two or more electrodes and one or more sources of water flow. The electrically conductive electrodes imbedded in the treatment surface are connected to a battery-powered electrical source with controls to select the source voltage amplitude, voltage frequency, pulse frequency, and other characteristics to achieve the desired physiological effects. The device is connected to a water source with selectable temperature and flow rate, with aeration to facilitate more gentle and uniform water flow over the treatment area.