GUNNES, Soelvi,BJOERNSTAD, Vidar,KOCH, Torben,MELANDER, Claes,MÃNSSON, Martin
申请号：
HUE14704292
公开号：
HUE034562T2
申请日:
2014.01.09
申请国别(地区):
HU
年份:
2018
代理人:
摘要：
Disclosed herein is a composition comprising at least one polymyxin or a salt thereof represented by formula (I) wherein R1 is an aliphatic linear or branched C6-C10 acyl group, or (I&prime；) R5 is &mdash；CH(CH3)2, &mdash；CH2CH(CH3)2, &mdash；CH(CH3)CH2CH3, or &mdash；CH2C6H5； R6 is &mdash；CH(CH3)2, &mdash；CH2CH(CH3)2, or &mdash；CH(CH3)CH2CH3； each of R2, R3, R4, R7 and R8 is either &mdash；(CH2)XCH2NH2 or &mdash；(CH2)xCH2N(CH2SO3M)2； wherein x is 0 or 1； wherein M is a monovalent cation； and wherein at least three of R2, R3, R4, R7 and R are &mdash；(CH2)xCH2N(CH2SO3M)2.
