James Yoo,Joel Stitzel,Anthony Atala,George Christ
申请号：
US11279671
公开号：
US09493735B2
申请日:
2006.04.13
申请国别(地区):
US
年份:
2016
代理人:
摘要：
A method of producing organized skeletal muscle tissue from precursor muscle cells in vitro comprises: (a) providing precursor muscle cells on a support in a tissue media then (b) cyclically stretching and relaxing the support at least twice along a first axis during a first time period and then (c) optionally but preferably maintaining the support in a substantially static position during a second time period and then (d) repeating steps (b) and (c) for a number of times sufficient to enhance the functionality of the tissue formed on the support and/or produce organized skeletal muscle tissue on the solid support from the precursor muscle cells.
