HADIDA-RUAH, SARA SABINA,ANDERSON, COREY,ARUMUGAM, VIJAYALAKSMI,ASGIAN, IULIANA LUCI,BEAR, BRIAN RICHARD,TERMIN, ANDREAS P.,JOHNSON, JR., JAMES PHILIP
申请号：
PE0015722015
公开号：
PE17812015A1
申请日:
2014.01.29
申请国别(地区):
PE
年份:
2015
代理人:
摘要：
The Invention relates to compounds of the formula piridonamida L and I or its pharmaceutically acceptable salts, g x - Rx, X is link or c1-c6 alkyl X is h r1 is H, halogen R2 is CN, h R3 is C1 - C6 alkyl R4 is H, halogen R8 and R9 are c1-c6 alkyl or Halogen p is 0 - 3. They are useful as inhibitors of sodium channels. It also relates to a pharmaceutically compositions.La invencion se refiere a compuestos de piridonamida de la formula l y I o sus sales farmaceuticamente aceptables, que G es X-Rx, X es enlace o alquilo C1-C6 RX es H R1 es H, halogeno R2 es CN, H R3 es alquilo C1-C6 R4 es H, halogeno R8 y R9 son halogeno o alquilo C1-C6 p es 0-3. Son utiles como inhibidores de los canales de sodio. Tambien se refiere a una composiciones farmaceuticamente.
