The Research Foundation for The State University of New York;Chem-Master International, Inc.
发明人:
申请号:
EP10775624.9
公开号:
EP3206488B1
申请日:
2010.05.14
申请国别(地区):
EP
年份:
2019
代理人:
摘要:
This invention provides a compound having the structure wherein α, &bgr;, X, Y, and R1-R11 are defined herein. This invention also provides a pharmaceutical composition comprising the above compounds, a method of inhibiting the activity and/or levels of a matrix metalloproteinase (MMP), a method of inhibiting the production of a cytokine in a population of cells, a method of inhibiting the production of a growth factor in a population of cells, and a method of inhibiting NF&kgr;-B activation in a population of cells.