#$%^&*AU2014202149A120140515.pdf#####LOCAL DELIVERY OF WATER-SOLUBLE OR WATER-INSOLUBLE THERAPEUTIC AGENTS TO THE SURFACE OF BODY LUMENS ABSTRACT In a first aspect there is disclosed a medical disposable device (110). The medical disposable device (110) comprises an expandable structure (112) having an outer surface and an amphiphilic polymer coating (114) disposed on the outer surface of the expandable structure. The amphiphilic polymer coating comprises an amphiphilic polymer or co-polymer complexed with iodine and a hydrophobic therapeutic agent, the amphiphilic polymer or co-polymer selected from the group consisting of hydroxypropyl cellulose (HPC), poly (methyl vinyl etheralt-maleic acid monobutyl ester), and poly (methyl vinyl ether-alt-maleic acid monoethyl ester).