The Royal Institution for the Advancement of Learning/McGill University;The Hospital for Sick Children
发明人:
Howell, Lynne,Baker, Perrin,Alnabelseya, Noor,Bamford, Natalie,Little, Dustin,Sheppard, Donald,Snarr, Brendan,Lee, Mark Jae
申请号:
AU2015271666
公开号:
AU2015271666A1
申请日:
2015.06.05
申请国别(地区):
AU
年份:
2017
代理人:
摘要:
The present disclosure relates to methods of treating or preventing a biofilm-related infection and methods of preventing and treating biofilm formation on indwelling medical devices, implants, and non-medical surfaces comprising administering at least one soluble microbial protein that is encoded by an exopolysaccharide biosynthetic operon or functional gene cluster, wherein the protein comprises a glycosyl hydrolase domain. The present disclosure further provides particular soluble glycosyl hydrolases and compositions thereof.