The Royal Institution for the Advancement of Learning/McGill University;The Hospital for Sick Children
发明人:
Lynne Howell,Perrin Baker,Noor Alnabelseya,Natalie Bamford,Dustin Little,Donald Sheppard,Brendan Snarr,Mark Jae Lee
申请号：
US15316394
公开号：
US20170216410A1
申请日:
2015.06.05
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present disclosure relates to methods of treating or preventing a biofilm-related infection and methods of preventing and treating biofilm formation on indwelling medical devices, implants, and non-medical surfaces comprising administering at least one soluble microbial protein that is encoded by an exopolysaccharide biosynthetic operon or functional gene cluster, wherein the protein comprises a glycosyl hydrolase domain. The present disclosure further provides particular soluble glycosyl hydrolases and compositions thereof.
