Deepak Tiwari,George Owoo,Rekha Nayak,Kenneth E. Burhop
申请号：
US11752103
公开号：
US08722736B2
申请日:
2007.05.22
申请国别(地区):
US
年份:
2014
代理人:
摘要：
Disclosed are concentrate esmolol injection essentially free from other related esters of esmolol and diluted esmolol compositions. The concentrate esmolol formulation includes from about 25-1000 mg/ml of esmolol and about 1-25% w/v of benzyl alcohol and the combination thereof. The compositions can also be used as multi-dose compositions. The present invention also discloses diluted, ready-to-use compositions of esmolol prepared by dilution of the present invention concentrates. Also disclosed are methods of making and using the ready-to-use compositions of the present invention.
