The invention relates to a process for the production of nanocrystals or amorphous nanoparticles of actives (nanomaterials), especially from the peels of grapes. According to the process of the invention, a dispersion of a micrometer-sized material in a solution of surfactant or a steric stabilizer is provided. The macrosuspension is then stirred for at least 1 minute at a rotational speed above 500 rpm. This stirring is effected using a rotor-stator mixer. Further, the mixture is passed through a jet stream or piston-gas type high pressure homogenizer. The process according to the invention is very economical and takes place under mild conditions. This excludes or minimizes any chemical decomposition. The nanomaterials according to the invention may be incorporated into formulations for use as nutraceutical, nutritional supplement, or as supportive treatment in medical therapy.