594351 Disclosed is a method of changing a molecular structure of a biomass feedstock, the method comprising: converting a treated biomass feedstock to a product, utilizing a microorganism, the treated biomass feedstock having been prepared by treating a biomass feedstock having a bulk density of less than about 0.5 g/cm3 using a treatment method selected from the group consisting of radiation, sonication, pyrolysis, and oxidation, wherein said treating comprises irradiating with an electron beam.