The present invention is directed to a method for treating cystic fibrosis. The method comprises the steps of: identifying a patient suffering from cystic fibrosis, applying about 0.8-3 mL of a solution comprising about 18-65 mg/mL of denufosol into a medication reservoir of an nebulizer to achieve a target loading dose of denufosol of about 25-52 mg denufosol per dosing regimen, nebulizing the solution by passing through holes of an vibrating mesh device equipped with an oscillating membrane in the nebulizer, and delivering an inhaled respiratory dose of 20-33 mg to the lungs of the patient by inhalation within 3-9 minutes.本発明は、嚢胞性線維症の治療方法を目的とする。当該方法は、嚢胞性線維症に罹患するヒト患者を同定する工程、デヌホソルを約18-65 mg/mL含む溶液の約0.8-3 mLを噴霧器の薬物リザーバーに適用し、投与計画あたり約25-52 mgのデヌホソルの標的負荷投与量を達成する工程、噴霧器中の振動膜が備わった振動するメッシュ装置の穴を通すことによって溶液を噴霧する工程、及び吸入によって吸入呼吸用量20-33 mgのデヌホソルを患者の肺へ3-9分内で送達する工程、を含む。
