KRISHNAMOORTHY, RAMESH,EVANS, CAROLE M.,BURKE, BRIAN J.,SCHABERG, AMY E.,COADY, THOMAS G.
申请号:
EP11833157
公开号:
EP2627336A4
申请日:
2011.10.06
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
The present invention is directed to a method for treating cystic fibrosis. The method comprises the steps of: identifying a patient suffering from cystic fibrosis, applying about 0.8-3 mL of a solution comprising about 18-65 mg/mL of denufosol into a medication reservoir of an nebulizer to achieve a target loading dose of denufosol of about 25-52 mg denufosol per dosing regimen, nebulizing the solution by passing through holes of an vibrating mesh device equipped with an oscillating membrane in the nebulizer, and delivering an inhaled respiratory dose of 20-33 mg to the lungs of the patient by inhalation within 3-9 minutes.