The Trustees of Columbia University in the City of New York
发明人:
Gillette, Brian,Sia, Samuel
申请号：
AU2013299377
公开号：
AU2013299377A1
申请日:
2013.08.12
申请国别(地区):
AU
年份:
2015
代理人:
摘要：
Provided are methods, pharmaceutical compositions, and kits for treatment of a metabolic condition, including obesity and type 2 diabetes by administration of a therapeutically effective amount of a cell or tissue preparation such as brown adipose microtissues to a subject, where the microtissues comprise adipose stem cells and endothelial cells. Modified approaches to creating brown adipose tissue involve differentiation of explanted white adipose tissue rather than isolation and expansion of adipose stems cells or endothelial cells and formation and differentiation of 3D cell aggregates.
