BROWN, PAMELA,DAWSON, MICHAEL,SIMONOVIC, MONA,BOAKES, STEVEN,DUPERCHY, ESTHER,STANWAY, STEVEN JAMES,WILSON, ANTOINETTE,MOSS, STEPHEN FREDERICK
申请号:
CA2968902
公开号:
CA2968902A1
申请日:
2015.11.26
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
The present invention provides a compound of formula (I), and its use in methods of treatment, including the treatment of bacterial infections. Methods for the preparation of the compound of formula (I) are also provided. The compound of formula (I) has the structure shown below, where -R6 and -R7 are each together with the carbonyl group and nitrogen alpha to the carbon to which it is attached an amino acid residue, except that R6 together with the carbonyl group and nitrogen alpha to the carbon to which it is attached is not a phenylalanine, leucine or valine residue and/or -R7 together with the carbonyl group and nitrogen alpha to the carbon to which it is attached is not a leucine, iso-leucine, phenylalanine, threonine, valine or nor-valine residue, and -T, -A1, -A2, -A3 and -R10 are as discussed in the application: