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Process for manufacturing spherical particles of pharmaceuticals
专利权人:
GLATT GMBH
发明人:
JACOB, MICHAEL,GRAVE, ANNETTE,NOWAK, REINHARD
申请号:
DK06776684
公开号:
DK1915135T3
申请日:
2006.08.08
申请国别(地区):
DK
年份:
2013
代理人:
摘要:
The invention relates to a method for producing particles with a length-width ratio of less than about 1.4 from a pharmaceutical substance, which method includes the following stages, that is: (a) provision of a melt of the pharmaceutical substance; (b) production of droplets of the melt by spraying into a processing chamber; (c) repeated guiding of solid particles past sprayed droplets in the processing chamber with the aid of a process gas jet which is guided in a defined way and whose temperature is fixed, depending on the solidification point of the melt, so that at least some of the droplets come into contact with particles and solidify thereon; (d) removal of particles from the processing chamber as a function of the particle size. The invention further relates to particles of pharmaceutical substances and the use thereof.
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