The invention relates to the use of cells of an in vitro cell culture for the production of viruses. Thereby, the cells are avian epithelial cells chosen from at least one of the cell cultures deposited under accession numbers DSM ACC3345, DSM ACC3346, DSM ACC3347, DSM ACC3348, DSM ACC3349 at Leibniz-Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH on December 12, 2018. The invention further relates to related manufacturing methods.