A compound selected from Formula ** Formula ** and its salts, where: L is O, S, C (>； = O) or CHR14； Y is N or CR4； Z is N or CR3, where at least one of G or Z is not N； G is N or CR11； R1 is a heteroaryl ring represented by the formula ** Formula ** D1 is S, O or N； D2 is N or CR12； D3 is S, O or CR13； R2 is aryl, heteroaryl, saturated or partially unsaturated cycloalkyl, or saturated or partially unsaturated heterocyclyl, wherein said aryl, heteroaryl, cycloalkyl and heterocyclyl are monocyclic or bicyclic and are optionally substituted with one or more groups independently selected from C1-C6 alkyl, alkenyl C2-C6, C2-C6 alkynyl, saturated or partially unsaturated C3-C6 cycloalkyl, saturated or partially unsaturated C1-C6 heterocyclyl, aryl, heteroaryl, F, Cl, Br, I, CF3, CN, NO2, OR6, C (>； = O) R6, C (>； = O) OR6, OC (>； = O) R6, O (CH2) nC (>； = O) OR6, O (CH2) nC (>； = O) NR6R7, C (>； = O ) NR6R7, NR6R7, NR6C (>； = O) R7, SR6, S (O) R6 and S (O) 2R6, and wherein said alkyl, alkenyl, alkynyl, cycloalkyl, heterocyclyl, aryl and heteroaryl are optionally substituted with one or more groups independently selected from oxo, C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, saturated or partially unsaturated C3-C6 alkynyl, saturated or partial Vn-heterocyclyl C1-C6 unsaturated mind, Vn-aryl, Vn-heteroaryl, Vn-F, Vn-Cl, Vn-Br, Vn-I, Vn-CF3, Vn-CN, Vn-OR8, Vn-C (>； = O) R8, Vn -C (>； = O) OR8, Vn-OC (>； = O) R8, Vn-C (>； = O) NR8R9, Vn-NR8R9, Vn-NR8C (>； = O) R9, Vn-SR8, Vn-S (O) R8 and Vn-S (O) 2R8； R3 is H, C1-C12 alkyl, C2-C12 alkenyl, C2-C12 alkynyl, saturated or partially unsaturated C3-C12 cycloalkyl, saturated or partially unsaturated C1-C12 heterocyclyl, aryl, heteroaryl, F, Cl, Br, I, CN , OR6, C (>； = O) R6, C (>； = O) OR6, OC (>； = O) R6, C (>； = O) NR6R7, OC (>； = O) NR6R7, OC (>； = S) NR6R7 , NR6R7, NR6C (>； = O) R7, SR6, S (O) R6, S (O) 2R6 or S (O) 2NR6R7, wherein said alkyl, alkenyl, alkynyl, cycloalkyl, heterocyclyl, a
