1. A process for the production of liposome preparation comprising: a) providing a first liposome preparation consisting of a suspension of liposomes in an aqueous phase, wherein the liposomes comprise at least one membrane, wherein the membrane limits encapsulated in liposomes volume of the aqueous phase and the aqueous phase contains at least one osmotically active substance and has an initial total osmolarity O, wherein the first liposome preparation contains at least one active substance or a cosmetic in the liposome membranes , B) thereafter receiving osmolar gradient in the aqueous phase of said formulation, wherein the aqueous phase osmolality outside liposome encapsulated volume, O, lower osmolarity of the aqueous phase inside the liposome-encapsulated volume, O, to produce a second liposome preparation and wherein the liposomal formulation comprises at least one active substance or a cosmetic in the liposome membrane, c) optionally, dehydrating the second liposome preparation to obtain a dehydrated preparation and d) optionally optionally rehydrating the dehydrated preparata.2. The method of claim 1, wherein step b) is carried out by reducing total osmolarity Ovodnoy initial phase liposome preparation in step a) to obtain a stress liposome preparation with a total osmolarity O is lower than the osmolarity of O.3. A method according to Claim. 1 or 2, wherein step b) is carried out by diluting the liposome preparation from step a) an aqueous medium having an osmolarity which is lower than O.4. A method according to Claim. 1 or 2, wherein the b) step is conducted by dialysis of the drug with1. Способ производства липосомального препарата, включающий:а) получение первого липосомального препарата, состоящего из суспензии липосом в водной фазе, причем липосомы содержат, по меньшей мере, одну мембрану, причем мембрана ограничивает инкапсулированный в липосомы объем водной фазы, и водная фаза содержит, по меньшей мере, одно осмотически активное вещество и имеет исх
