Michael Meehl,Sandra Rios,Sujatha Gomathinayagam,Huijuan Li,Piotr Bobrowicz
申请号：
US13504528
公开号：
US20120213728A1
申请日:
2010.10.25
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Compositions comprising granulocyte-colony stimulating factor (GCSF) produced in a strain of Pichia pastoris glycoengineered to produce a GCSF wherein greater than 18% of the molecules comprise an 0-glycan with one mannose per (0-glycan is described. In particular aspects, the GCSF is PEGylated at the JV-terminus.
