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INHIBITEURS DE L'AUTOTAXINE
专利权人:
CANCER RESEARCH TECHNOLOGY LIMITED
发明人:
BLUM, FRANCESCA,CARR, JAMES LINDSAY,SHAH, PRITOM,DEL MAR JIMENEZ QUESADA, MARIA,FARRE GUTIERREZ, IRENE
申请号:
CA2974265
公开号:
CA2974265A1
申请日:
2016.02.04
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
The present invention relates to compounds of formula (I): wherein R1, R2, R3, R4a, R4b, R4C, R4d, L, A, Q, W and HET are each as defined herein. The compounds of the present invention are inhibitors of autotaxin (ATX) enzyme activity. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of proliferative disorders, such as cancer, as well as other diseases or conditions (e.g. fibrosis) in which ATX activity is implicated.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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