VELPANDI AYYAVOO,THANADAVARAYAN NAGASHUNMUGAM,DAVID B. WEINER
申请号:
PT08075892
公开号:
PT2044950E
申请日:
1998.09.18
申请国别(地区):
PT
年份:
2012
代理人:
摘要:
The present invention is directed to nucleic acid molecules encoding attenuated, non-functional virion infectivity factor ( vif ) proteins. The nucleic acid molecules of the invention are inserted into recombinant expression vectors and administered to mammals in order to induce a cellular and humoral immune response to the encoded protein product.