The purpose of the invention is to provide a composition that has high biological safety and contributes to the activation of PGC-1[alpha]. Also, the purpose of the invention is to provide a use for said composition for activating PGC-1[alpha] and a method for activating PGC-1[alpha]. It was found that a specific compound, among naturally occurring compounds, has a PGC-1[alpha] activating action. The invention provides a novel and effective means contributing to improving endurance, increasing muscle size, suppressing obesity, reducing stress, improving sugar metabolic functions, and suppressing muscular atrophy.本發明係以提供生物安全性高且賦予PGC-1α之活性化的組成物為目的。又以提供欲使PGC-1α活性化的組成物之使用及使PGC-1α活性化的方法為目的。 本發明為發現由來自天然物的化合物之中的特定化合物具有PGC-1α之活性化作用。故本發明提供一種對於持久力的提高、肌肉肥大、肥胖抑制、壓力輕減、糖代謝功能的改善及肌肉萎縮抑制有貢獻的效果且新穎的方法。