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MAO Inhibitors and Their Conjugates as Therapeutics For The Treatment of Brain Cancer
专利权人:
发明人:
Jean C. Shih,Florence M. Hofman,Thomas C. Chen
申请号:
US14615416
公开号:
US20160339034A9
申请日:
2015.02.05
申请国别(地区):
US
年份:
2016
代理人:
摘要:
A pharmaceutical composition and method for treating brain cancer are provided. The method includes administering to a patient in need thereof an effective amount of one or more compounds that include moclobemide, clorgyline, clorgylines Near-infra-red dye Monoamine Oxidase Inhibitor (NMI), and MHI 148-clorgyline, and their salt thereof. The composition and method are particularly effective in reducing the size of glioblastomas that are temozolomide (TMZ) resistant.
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