A dual chamber combined container-syringe (100) which includes: an outer casing (10) which forms a cylinder shape around an axis (O), and has a bypass portion formed by an outward bulging of a part of an inner peripheral surface a hub lure lock (20) provided in a tip of the outer casing a finger grip (60) provided in a rear end of the outer casing a front stopper (30) that is fitted to a tip side of the bypass portion in the outer casing a middle stopper (40) that is fitted to a rear end side of the bypass portion in the outer casing and seals a pharmaceutical preparation (S) together with the front stopper (30) an end stopper (50) that is fitted to a rear end side of the middle stopper (40) in the outer casing and seals a liquid medicine (L) together with the middle stopper (40) and a plunger rod (70) that is inserted into the finger grip (60) and is connected to the end stopper (50) from the rear end side, wherein an inner peripheral surface of the finger grip (60) is formed with a female screw portion (64) that is twisted around the axis, and an outer peripheral surface of the plunger rod (70) is formed with a first male screw portion (73a) that is capable of being screwed into the female screw portion (64), when a part of the middle stopper (40), which is moved forward, enters the bypass portion (11) by pushing the plunger rod (70), a tip of the first male screw portion (73a), can come into contact with and can be screwed into a rear end of the female screw portion (64), and before the entire middle stopper (40) which is moved forward, enters the bypass portion (11) by rotating the plunger rod (70) according to the second male screw portion (73b) and the female screw portion (64) being screwed, the first male screw portion (73a) and the female screw portion (64) are unscrewed.
