VISCOMI, GIUSEPPE CLAUDIO,CAMPANA, MANUELA,FOLEGATTI, MAHENA,CANNATA, VINCENZO,RIGHI, PAOLO,ROSINI, GOFFREDO
申请号：
HK12103912.5
公开号：
HK1163663B
申请日:
2012.04.19
申请国别(地区):
HK
年份:
2015
代理人:
摘要：
Disclosed are rifamycin derivatives having antibacterial activities, wherein the compounds have the following general formula: wherein: R is hydrogen or acetyl； R1 and R2 are independently selected from the group consisting of hydrogen, (C1-4)alkyl, benzyloxy, mono- and di-(C1-3)alkylamino-(C1-4)alkyl, (C1-3)alkoxy, (C1-4)alkyl, hydroxy-methyl, hydroxy-(C2-4)-alkyl, and nitro or R1 and R2 taken together with two consecutive carbon atoms of the pyridine nucleus form a benzene ring optionally substituted by one or two methyl or ethyl groups and R3 is hydroxyalkyl(C1-4). In addition, processes to obtain these compounds are described.
